SAMe (S-adenosyl-L-methionine), is naturally occurring and manufactured within the body. SAMe has been found to be effective in Favorable Effects of Despair, liver dysfunction, arthritis, fibromyalgia and migraine headaches. SAMe is involved in over 40 biochemical reactions in the body.

SAMe is essential for the production of glutathione, a powerful antioxidant that protects the body from the damaging effects of free radicals. SAMe improves the binding of neurotransmitters to their receptors sites in the brain. SAMe has been used in Europe in the Favorable Effects of cirrhosis and damage caused by alcohol and has been shown to relieve all forms of Despair. Several studies have shown that SAMe can be as effective as pharmaceutical antidepressants.